| 货号 | 2339/10 |
| 别名 | 4-[3-[4[(2-Chlorophenyl)-9-methyl-6 |
| 供应商 | Tocris |
| 生物活性 | Potent, selective platelet-activating factor (PAF) receptor antagonist (Ki = 16.3 nM). Displays anti-inflammatory, antiangiogenic and anticancer activity. Inhibits growth and proliferation of MCF-7 breast cancer cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 455.96 |
| 分子式 | C22H22N5O2SCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol with gentle warming |
| CAS号 | 105219-56-5 |
| 参考文献 | Cellaiet al (2006) Growth inhibition and differentiation of human breast cancer cells by the PAFR antagonist WEB-2086. Br.J.Cancer 94 1637. PMID: 16721373. Sariahmetogluet al (1998) Effects of WEB 2086 on the protective role of preconditioning against arrhythmias in rats. Pharmacol.Res. 38 173. PMID: 9782066. Dentet al (1989) Characterization of PAF receptors on human neutrophils using the specific antagonist, WEB 2086. FEBS Lett. 244 365. PMID: 2537761. |