| 货号 | 1201/5 |
| 别名 | (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a- |
| 供应商 | Tocris |
| 生物活性 | Extensively used phorbol ester activator of protein kinase C; tumor promoter. Binds to PKC with a Ki value of 2.6 nM as measured by displacement of [3H]phorbol 12,13-dibutyrate binding in rat cortex synaptosomal membranes. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 616.83 |
| 分子式 | C36H56O8 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 16561-29-8 |
| 参考文献 | Murphyet al (1999) Structural determinants of phorbol ester binding in synaptosomes: pharmacokinetics and pharmacodynamics. Eur.J.Pharmacol. 381 77. PMID: 10528137. Hockbergeret al (1989) A diacylglycerol analogue reduces neuronal calcium currents independently of protein kinase C activation. Nature 338 340. PMID: 2922062. Castagnaet al (1982) Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J.Biol.Chem. 257 7847. PMID: 7085651. Merck Index 127487. |