3,3-cGAMP sodium salt ( )
货号：
5946/359U 基本售价：
3708.0 元 规格：
359 ug
产品信息
概述| 货号 | 5946/359U |
| 别名 | 3',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt |
性能| 供应商 | Tocris |
| 生物活性 | STING agonist. Reduces B cell proliferation and induces apoptosis of malignant B cells in vitro. Suppresses 5TGM1 multiple myeloma xenograft growth in immunodeficient mice, and induces leukemic regression in Eμ-TCL1 mice. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 718.37 |
| 分子式 | C20H22N10Na2 |
| 可溶性/溶解性 | Soluble to 10 mM in water |
| 参考文献 | Tanget al (2016) Agonist-mediated activation of STING induces apoptosis in malignant B cells. Cancer Res. 76 2137. PMID: 26951929. |
