3,3-cGAMP sodium salt ( )
货号:
5946/359U 基本售价:
3708.0 元 规格:
359 ug
产品信息
概述货号 | 5946/359U |
别名 | 3',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt |
性能供应商 | Tocris |
生物活性 | STING agonist. Reduces B cell proliferation and induces apoptosis of malignant B cells in vitro. Suppresses 5TGM1 multiple myeloma xenograft growth in immunodeficient mice, and induces leukemic regression in Eμ-TCL1 mice. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 718.37 |
分子式 | C20H22N10Na2 |
可溶性/溶解性 | Soluble to 10 mM in water |
参考文献 | Tanget al (2016) Agonist-mediated activation of STING induces apoptosis in malignant B cells. Cancer Res. 76 2137. PMID: 26951929. |