货号 | 5992/1 |
供应商 | Tocris |
生物活性 | Potent apelin receptor antagonist (Ki = 82 nM; IC50 = 93 nM). Antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1737.15 |
分子式 | C70H121N29O1 |
可溶性/溶解性 | Soluble to 2 mg/ml in water |
序列号 | CRPRLCKHCRPRLC (Modifications: Disulfide bridge: 1-6,9-14) |
参考文献 | Macalusoet al (2011) Discovery of a competitive apelin receptor (APJ) antagonist. ChemMedChem 6 1017. PMID: 21560248. |