| 货号 | 4625/10 |
| 别名 | (2S)-N-[[4-[(4,10-Dihydro-1-methylp |
| 供应商 | Tocris |
| 生物活性 | Potent non-peptide oxytocin receptor partial agonist (EC50 values are 33 nM and 850 nM for the oxytocin receptor and V2 vasopressin receptor respectively). Also a V1a vasopressin receptor antagonist (Ki = 330 nM). Active in vivo in a rat model of uterine response. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >97 % |
| 计算分子量 | 600.78 |
| 分子式 | C32H40N8O2 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO |
| 参考文献 | Frantzet al (2010) Subtlety of the structure-affinity and structure-efficacy relationships around a nonpeptide oxytocin receptor agonist. J.Med.Chem. 53 1546. PMID: 20104850. Pittet al (2004) Non-peptide oxytocin agonists. Bioorg.Med.Chem.Lett. 14 4585. PMID: 15357997. |