| 货号 | 1963/10 |
| 别名 | N-(6,8-Difluoro-2-methyl-4-quinolin |
| 供应商 | Tocris |
| 生物活性 | Selective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). Blocks orexin-A induced grooming following oral administration in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 356.37 |
| 分子式 | C19H18F2N4O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 288150-92-5 |
| 参考文献 | Langmeadet al (2004) Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor. Br.J.Pharmacol. 141 340. PMID: 14691055. Porter (2001) Advances in novel 7-TM receptors: non-peptide orexin-1 antagonists. Royal Society of Chemistry Meeting.. |