CTA 056 (10 MG)
货号：
4726/10 基本售价：
3648.5 元 规格：
10 mg
产品信息
概述| 货号 | 4726/10 |
| 别名 | 1,5-Dihydro-7-(phenylmethyl)-1-[3-(1-piperidinyl)propyl]-2-[4-(4-pyridinyl)phenyl]-6H-imidazo[4,5-g]quinoxalin-6-one |
性能| 供应商 | Tocris |
| 生物活性 | Interleukin-2-inducible T-cell kinase (ITK) inhibitor (IC50 values are 0.1, 0.4 and 5 μM for ITK, BTK and ETK, respectively). Inhibits growth of cancer cells expressing ITK, including MOLT-4 and Jurkat cells in vitro. Induces apoptosis in Jurkat cells. Inhibits MOLT-4 xenograft tumor growth in mice. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 554.68 |
| 分子式 | C35H34N6O |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO with gentle warming |
| 参考文献 | Guoet al (2012) Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Mol.Pharmacol. 82 938. PMID: 22899868. |
