| 货号 | 2417-5 |
| 描述 | GW 4869 is a cell-permeable, non-competitive inhibitor of neutral sphingomyelinases (IC₅₀ = 1 μM), but does not affect acid sphingomyelinase activity. It inhibits TNF-α-mediated sphingomyelin hydrolysis (100% inhibition at 20 μM) and TNF-α-induced cell death in MCF7 cells without interfering with activation of NF-κB or glutathione depletion in response to TNF. |
| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20 ̊C |
| 外观 | Pale yellow solid |