| 货号 | 1843/1 |
| 供应商 | Tocris |
| 生物活性 | Potent and selective somatostatin sst2 receptor antagonist. pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1197.35 |
| 分子式 | C56H68N12O14S2 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 183658-72-2 |
| 序列号 | FCYWKTCY (Modifications: Phe-1 = Ac-(4-nitro)Phe, Cys-2 = D-Cys, Trp-4 = D-Trp, Tyr-8 = D-Tyr & C-terminal amide, Disulfide bridge between 2 - 7) |
| 参考文献 | Hannonet al (2002) Drug design at peptide receptors. Somatostatin receptor ligands. J.Mol.Neurosci. 18 15. PMID: 11931345. Feniuket al (2000) Selective somatostatin sst2 receptor blockade with the novel cyclic octapeptide, CYN-154806. Neuropharmacology 39 1443. PMID: 10818260. Basset al (1996) Identification and characterization of novel somatostatin antagonists. Mol.Pharmacol. 50 709. PMID: 8863814. |