Thiamet G (10 MG)
货号：
4390/10 基本售价：
3499.8 元 规格：
10 mg
产品信息
概述| 货号 | 4390/10 |
| 别名 | (3aR,5R,6S,7R,7aR)-2-(Ethylamino)-3a,6,7,7a-tetrahydro-5-(hydroxymethyl)-5H-pyrano[3,2-d]thiazole-6,7-diol |
性能| 供应商 | Tocris |
| 生物活性 | Potent, selective inhibitor of O-GlcNAcase (Ki = 21 nM for human O-GlcNAcase). Decreases the phosphorylation of tau protein in vivo. Orally bioavailable and blood brain barrier permeable. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 248.3 |
| 分子式 | C9H16N2O4 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Yuzwaet al (2008) A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo. Nat.Chem.Biol. 4 483. PMID: 18587388. |
