货号 | 5633/1 |
别名 | 2-Thiouridine-5'-O-(α,β-methylene)diphosphate trisodium salt |
供应商 | Tocris |
生物活性 | Potent and selective P2Y14 receptor agonist (EC50 = 0.92 nM). Exhibits >2000-fold selectivity over P2Y6. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 484.2 |
分子式 | C10H13N2Na3< |
可溶性/溶解性 | Soluble to 45 mM in water |
参考文献 | Lazarowskiet al (2015) UDP-sugars as extracellular signaling molecules: cellular and physiologic consequences of P2Y14 receptor activation. Mol.Pharmacol. 88 151. PMID: 25829059. Daset al (2010) Human P2Y14 receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups J.Med.Chem. 53 471. PMID: 19902968. |