| 货号 | 2502/1 |
| 别名 | 5-Iodouridine-5'-O-diphosphate trisodium salt; 5-Iodo-UDP trisodium salt |
| 供应商 | Tocris |
| 生物活性 | Selective P2Y6 agonist (EC50 = 0.015 μM at the hP2Y6 receptor). Displays no activity at other P2Y subtypes. Exerts a cytoprotective effect in an in vivo mouse model of hindlimb skeletal muscle ischemia/reperfusion injury. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >95 % |
| 计算分子量 | 596 |
| 分子式 | C9H10IN2Na3O12P2 |
| 可溶性/溶解性 | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
| CAS号 | 911391-37-2 |
| 参考文献 | Jacobsonet al (2009) Development of selective agonists and antagonists of P2Y receptors. Purinerg.Sig. 575. Mamedovaet al (2008) Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation. Pharmacol.Res. 58 232. PMID: 18805489. Besadaet al (2006) Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. J.Med.Chem. 49 5532. PMID: 16942026. |