| 货号 | 4860/10 |
| 别名 | N-[4-[[(3,4-Dimethyl-5-isoxazolyl)a |
| 供应商 | Tocris |
| 生物活性 | Selective GPR55 antagonist (IC50 = 221 nM). Exhibits >27-, >145- and >145-fold selectivity for GPR55 over CB1, GPR35 and CB2, respectively. Inhibits ERK signaling in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 527.59 |
| 分子式 | C28H25N5O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Kotsikorouet al (2013) Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry 52 9456. PMID: 24274581. Heynen-Genelet al (2010) Screening for selective ligands for GPR55 - antagonists. Probe Reports from the NIH Molecular Libraries Program. PMID: 22091481. |