MI 14 (10 MG)
货号:
5604/10 基本售价:
3499.8 元 规格:
10 mg
产品信息
概述货号 | 5604/10 |
别名 | N-[2-[[6-Chloro-3-[3-[(dimethylamino)sulfonyl]phenyl]-2-methylimidazo[1,2-b]pyridazin-8-yl]amino]ethyl]acetamide |
性能供应商 | Tocris |
生物活性 | Potent and selective PI 4-K IIIβ inhibitor (IC50 = 54 nM). Exhibits >1,800-fold selectivity for PI 4-K IIIβ over PI 4-K IIIα and PI 4-K IIα, respectively. Exhibits antiviral activity against single-stranded positive sense RNA viruses in HeLa cell-based assays. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 450.94 |
分子式 | C19H23ClN6O3 |
可溶性/溶解性 | Soluble to 20 mM in DMSO |
参考文献 | Mejdrováet al (2015) Highly selective phosphatidylinositol 4-kinase IIIβ inhibitors and structural insight into their mode of action. J.Med.Chem. 58 3767. PMID: 25897704. |