货号 | 5200/10 |
别名 | 4-(2-Aminoethyl)-6-chloro-7-hydroxy |
供应商 | Tocris |
生物活性 | pH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 335.76 |
分子式 | C11H11N2ClO3 |
可溶性/溶解性 | Soluble to 20 mM in water with gentle warming and to 100 mM in DMSO |
参考文献 | Rodriguezet al (2013) Fluorescent dopamine tracer resolves individual dopaminergic synapses and their activity in the brain. Proc.Natl.Acad.Sci.U.S.A. 110 870. PMID: 23277566. Sameset al (2013) Visualizing neurotransmitter secretion at individual synapses. ACS Chem.Neurosci. 4 648. PMID: 23862751. Leeet al (2010) Development of pH-responsive fluorescent false neurotransmitters. J.Am.Chem.Soc. 132 8828. PMID: 20540519. |