| 货号 | 21081-1mL |
| 描述 | Mouse neutrophil gelatinase-associated lipocalin (NGAL) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. 24p3 was observed to be dramatically upregulated in kidney cell cultures infected with SV40 and subsequently identified as a lipocalin.1,2 Unlike human NGAL, it is an acute phase protein upregulated in the liver, but like its mammalian homologs it is upregulated and secreted by the kidney in response to ischemic or nephrotoxic injury.3,4 It is also upregulated in the involuting uterus and mammary gland.5 |
| 别名 | Lipocalin-2;Neutrophil gelatinase-associated lipocalin;Oncogene 24p3; |
| 应用 | ELISA |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Hraba-Renevey, S.,Turler, H.,Kress, M., et al. SV40-induced expression of mouse gene 24p3 involves a post-transcriptional mechanism. Oncogene 4(5), 601-608 (1989). 2.Flower, D.R.,North, A.C. and Attwood, T.K. Mouse oncogene protein 24p3 is a member of the lipocalin protein family. Biochem. Biophys. Res. Commun. 180(1), 69-74 (1991). 3.Liu, Q. and Nilsen-Hamilton, M. Identification of a new acute phase protein.. J. Biol. Chem. 270(38), 22565-22570 (1995). 4.Mishra, J.,Ma, Q.,Prada, A., et al. Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J. Am. Soc. Nephrol. 14, 2534-2543 (2003). 5.Ryon, J.,Bendickson, L. and Nilsen-Hamilton, M. High expression in involuting reproductive tissues of uterocalin/24p3, a lipocalin and acute phase protein. Biochem. J. 367, 271-277 (2002). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | 2-8 |
| 稳定性 | ≥ 6 months |
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