| 货号 | 2672/10 |
| 别名 | N-[[(4S)-Hexahydro-1-methyl-2,6-dio |
| 供应商 | Tocris |
| 生物活性 | Synthetic thyrotropin-releasing hormone (TRH) analog. Displays ~ 30 - 100-fold more potent CNS activity and ~ 50-fold weaker endocrine activity than TRH. Antinociceptive and neuroprotective. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >96 % |
| 计算分子量 | 405.41 |
| 分子式 | C17H23N7O5 |
| 可溶性/溶解性 | Soluble to 50 mM in water |
| CAS号 | 103300-74-9 |
| 参考文献 | Tanabeet al (2007) The synthetic TRH analogue taltirelin exerts modality-specific antinociceptive effects via distinct descending monoaminergic systems. Br.J.Pharmacol. 150 403. PMID: 17220907. Urayamaet al (2002) Neuroprotective effect and brain receptor binding of taltirelin, a novel thyrotropin-releasing hormone (TRH) analogue, in transient forebrain ischemia of C57BL/6J mice. Life Sci. 72 601. PMID: 12467901. Suzukiet al (1990) Synthesis and central nervous system actions of thyrotropin-releasing hormone analogues containing a dihydroorotic acid moiety. J.Med.Chem. 33 2130. PMID: 2115588. |