货号 | 5031/500U |
供应商 | Tocris |
生物活性 | Synthetic version of amylin (Cat. No. 3418). Exhibits high affinity for amylin, CGRP and calcitonin receptors (Ki values are 0.023, 3.8 and 5.1 nM respectively). Reduces postprandial hyperglycemia; also inhibits gastric emptying. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 3949.42 |
分子式 | C171H267N51O |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
序列号 | Lys-Cys-Asn-Thr-Ala-Thr-Cys-Al |
参考文献 | Hoogwerfet al (2008) Pramlintide, the synthetic analogue of amylin: phsyiology, pathophysiology, and effects on glycemic control, body weight, and selected biomarkers of vascular risk. Vasc.Health Risk Manag. 4 355. PMID: 18561511. Younget al (1996) Preclinical pharmacology of pramlintide in the rat: comparisons with human and rat amylin. Drug Dev.Res. 37231. |