| 货号 | 2440/10 |
| 别名 | 1-[3-[N-(5-Bromopyridin-2-yl)-N-(3, |
| 供应商 | Tocris |
| 生物活性 | Somatostatin sst4 receptor agonist that displays > 100-fold selectivity over sst2 receptors (Ki values are 6 and 621 nM for sst4 and sst2 receptors respectively). Potently inhibits forskolin-induced cAMP accumulation (EC50 = 26 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 556.35 |
| 分子式 | C22H25N6Cl2SBr |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 50 mM in ethanol |
| CAS号 | 199522-35-5 |
| 参考文献 | Liuet al (1999) 2-pyridylthioureas: novel nonpeptide somatostatin agonists with SST4 selectivity. Curr.Pharm.Des. 5 255. PMID: 10101224. Liuet al (1998) Nonpeptide somatostatin agonists with sst4 selectivity: synthesis and structure-activity relationships of thioureas. J.Med.Chem. 41 4693. PMID: 9822540. |