| 货号 | 5154/1 |
| 供应商 | Tocris |
| 生物活性 | Humanin analog; increases glucose stimulated insulin secretion and glucose metabolism in vivo andin vitro. Also enhances glucose sensing in βTC3 cells and lowers blood glucose in Zucker diabetic fatty rats. Prevents endothelial dysfunction and delays progression of atherosclerosis in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 2581.13 |
| 分子式 | C112H198N34O |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| 序列号 | MAPRGASCLLLLTGEIDLPVKRRA |
| 参考文献 | Kuliawatet al (2013) Potent humanin analog increases glucose-stimulated insulin secretion through enhanced metabolism in the β cell. FASEB J. 27 4890. PMID: 23995290. Ohet al (2011) Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice. Atherosclerosis. 219 65. PMID: 21763658. Muzumdaret al (2009) Humanin: a novel central regulator of peripheral insulin action. PLoS One. 4 e6334. PMID: 19623253. |