货号 | 1898/500U |
供应商 | Tocris |
生物活性 | Endogenous peptide activator of intestinal guanylyl cyclase; secreted mainly by the gastrointestinal mucosa. Regulates water and electrolyte transport in intestinal and renal epithelia. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1458.65 |
分子式 | C58H87N15O21 |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
序列号 | PGTCEICAYAACTGC (Modifications: Cys-15 = C-terminal OH, Disulfide Bridge between 4 - 2, 7 - 5) |
参考文献 | Beltowski (2001) Guanylin and related peptides. J.Physiol.Pharmacol. 52 351. PMID: 11596856. Nokiharaet al (1997) Synthesis, solution structure, binding activity, and cGMP activation of human guanylin and its disulfide isomer. Regul.Pept. 70 111. PMID: 9272623. Currieet al (1992) Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc.Natl.Acad.Sci.U.S.A. 89 947. PMID: 1346555. |