| 货号 | 3594/1 |
| 供应商 | Tocris |
| 生物活性 | GRK2 inhibitory polypeptide that specifically inhibits Gβγ activation of GRK2. Corresponds to the Gβγ-binding domain and acts as a cellular Gβγantagonist. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 3484.08 |
| 分子式 | C153H256N50O41S |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| CAS号 | 148505-03-7 |
| 序列号 | WKKELRDAYREAQQLVQRVPKMKNKPRS |
| 参考文献 | Danget al (2009) Two distinct mechanisms mediate acute μ-opioid receptor desensitization in native neurons. J.Neurosci. 29 3322. PMID: 19279269. Macrezet al (1997) A βγ dimer derived from G13 transduces the angiotensin AT1 receptor signal to stimulation of Ca2+ channels in rat portal vein myocytes. J.Biol.Chem. 272 23180. PMID: 9287322. Kochet al (1994) Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates Gβγ-mediated signaling. J.Biol.Chem. 269 6193. PMID: 8119963. |