DPPI 1c hydrochloride (10 MG)
货号：
2783/10 基本售价：
3351.1 元 规格：
10 mg
产品信息
概述| 货号 | 2783/10 |
| 别名 | 1-[[[(1-Hydroxymethyl)cyclopentyl]amino]acetyl]-2,5-cis-pyrrolidinedicarbonitrile hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50 = 104 nM) that displays selectivity over enzymes with DPP-like activity (IC50 > 30 μM). Increases plasma GLP-1 levels and improves glucose tolerance in diabetic mice following oral glucose challenge. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 312.8 |
| 分子式 | C14H20N4O2.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in water |
| CAS号 | 866396-34-1 |
| 参考文献 | Wrightet al(2006)cis-2-5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterization. J.Med.Chem. 49 3068. PMID: 16722626. |
