CID 755673 (10 MG)
货号:
3327/10 基本售价:
3351.1 元 规格:
10 mg
产品信息
概述货号 | 3327/10 |
别名 | 2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one |
性能供应商 | Tocris |
生物活性 | Selective protein kinase D (PKD) inhibitor (IC50 values are 0.182, 0.280, 0.227, >10, 15.3, 20.3, 40.5 and >50 μM at PKD1, PKD2, PKD3, PKC, CAK, PLK1, CAMKIIα and Akt respectively). Blocks PKD-mediated protein transport and inhibits prostate cancer cell proliferation, migration and invasion in vitro. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 217.22 |
分子式 | C12H11NO3 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 521937-07-5 |
参考文献 | Sharlowet al (2008) Potent and selective disruption of protein kinase D functionality by benzoxoloazepinolone. J.Biol.Chem. 283 33516. PMID: 18829454. |