货号 | 3671/10 |
别名 | 5-[[5-(4-Fluoro-2-hydroxyphenyl)-2- |
供应商 | Tocris |
生物活性 | Potent and selective inhibitor of PI 3-kinase γ(IC50 values are 33 and 935 nM for PI 3-Kγ and PI 3-Kαrespectively). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 305.28 |
分子式 | C14H8FNO4S |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
参考文献 | Pomelet al (2006) Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ. J.Med.Chem. 49 3857. PMID: 16789742. Condliffeet al (2005) Sequential activation of class IB and IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood 106 1432. PMID: 15878979. |