| 货号 | 2730/10 |
| 别名 | 5-[5,6,7,8-Tetrahydro-3,5,5,8,8-pen |
| 供应商 | Tocris |
| 生物活性 | Selective gonadotropin-releasing hormone (GnRH) receptor antagonist (Ki values are 2.2, 3.8 and 6.0 nM for mouse, rat and human receptors respectively). Suppresses testosterone and luteinising hormone (LH) levels in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >97 % |
| 计算分子量 | 491.62 |
| 分子式 | C30H37NO5 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| CAS号 | 263847-55-8 |
| 参考文献 | Andereset al (2003) Biological characterization of a novel, orally active small molecule gonadotropin-releasing hormone (GnRH) antagonist using castrated and intact rats. J.Pharmacol.Exp.Ther. 305 688. PMID: 12606616. Iatsimirskaiaet al (2002) Effect of testosterone suppression on the pharmacokinetics of a potent GnRH receptor antagonist. Pharm.Res. 19 202. PMID: 11883648. |