| 货号 | 3231/1 |
| 供应商 | Tocris |
| 生物活性 | N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. Acts as a formyl peptide receptor 1 (FPR1) ligand and stimulates neutrophil NADPH oxidase activation. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 2183.35 |
| 分子式 | C99H143N23O33 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in 20% acetonitrile / water |
| CAS号 | 284040-76-2 |
| 序列号 | QAWFIENEEQEYVQTVK (Modifications: Gln-1 = N-terminal amide) |
| 参考文献 | Rabiertet al (2007) The N-formyl peptide receptors and the anaphylatoxin C5a receptors: an overview. Biochimie 89 1089. PMID: 17428601. Karlssonet al (2005) Neutrophil NADPH-oxidase activation by an annexin AI peptide is transduced by the formyl peptide receptor (FPR), whereas an inhibitory signal is generated independently of the FPR family receptors. J.Leuko.Biol. 78762. Waltheret al (2000) A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR. Mol.Cell 5 831. PMID: 10882119. |