| 货号 | 1189/500U |
| 供应商 | Tocris |
| 生物活性 | Highly potent and selective ETB endothelin receptor agonist (Ki values are 0.18 and 970 nM at human ETB and ETA receptors respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 2006.35 |
| 分子式 | C96H140N20O2 |
| 可溶性/溶解性 | Soluble to 0.50 mg/ml in sodium bicarbonate (0.03M) |
| 序列号 | LMDKEAVYFAHLDIIW (Modifications: Leu-1 = N-terminal Ac) |
| 参考文献 | Iharaet al (1995) [3H]-BQ-123, a highly specific and reversible radioligand for the endothelin ETA receptor subtype. Eur.J.Pharmacol. 274 1. PMID: 7768260. Reynoldset al (1995) Pharmacological differences between rat and human endothelin B receptors. Biochem.Biophys.Res.Commun. 209 506. PMID: 7733918. Ekelundet al (1994) Effects of selective ETB-receptor stimulation on arterial, venous and capillary functions in cat skeletal muscle. Br.J.Pharmacol. 112 887. PMID: 7921617. Sakamotoet al (1993) Distinct subdomains of human endothelin receptors determine their selectivity to endothelinA-selective antagonist and endothelinB-selective agonists. J.Biol.Chem. 268 8547. PMID: 8473300. |