Senexin A (10 MG)
货号：
4875/10 基本售价：
3113.1 元 规格：
10 mg
产品信息
概述| 货号 | 4875/10 |
| 别名 | 4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitrile hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Cyclin-dependent kinase 8 (cdk8) inhibitor (IC50 = 280 nM). Also binds to cdk19 in an ATP-competitive manner. Inhibits p21-induced transcription. Reverses doxorubicin-induced tumor-promoting paracrine activities in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 310.78 |
| 分子式 | C17H14N4.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Porteret al (2012) Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities. Proc.Natl.Acad.Sci.U.S.A. 109 13799. PMID: 22869755. |
