| 货号 | 3407/1 |
| 供应商 | Tocris |
| 生物活性 | Potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Metabolically stable. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1140.35 |
| 分子式 | C57H81N13O12 |
| 可溶性/溶解性 | Soluble to 5 mg/ml in water |
| CAS号 | 185052-09-9 |
| 序列号 | KRPPGFSXI (Modifications: Lys-1 = N-terminal Ac, X = DβNal) |
| 参考文献 | Abdouhet al (2008) Retinal plasma extravasation in streptozotocin-diabetic rats mediated by kinin B1 and B2 receptors. Br.J.Pharmacol. 154 136. PMID: 18311190. Quintaoet al (2008) Neuropathic pain-like behavior after brachial plexus avulsion in mice: the relevance of kinin B1 and B2 receptors. J.Neurosci. 28 2856. PMID: 18337416. Gobeilet al (1996) Structure-activity studies of B1 receptor-related peptides. Hypertension. 28 833. PMID: 8901831. |