| 货号 | 4611/1 |
| 供应商 | Tocris |
| 生物活性 | Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1712.1 |
| 分子式 | C84H126N24O1 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| 序列号 | QRLFQVKGRR (Modifications: Gln-1 = Rhodamine-B) |
| 参考文献 | Forsmanet al (2012) Structural characterization and inhibitory profile of formyl peptide receptor 2 selective peptides descending from a PIP2-binding domain of gelsolin. J.Immunol. 189 629. PMID: 22706076. Cunninghamet al (2011) Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly. J.Biol.Chem. 276 43390. PMID: 11533030. |