| 货号 | 1917/1 |
| 供应商 | Tocris |
| 生物活性 | Endogenous peptide regulating blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function. Also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 2643 |
| 分子式 | C124H180N34O31 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 117505-80-3 |
| 序列号 | YKVNEYQGPVAPSGGFFLFRPRN (Modifications: Asn-23 = C-terminal amide) |
| 参考文献 | Mondalet al (2003) Neuromedin U acts in the cental nervous system to inhibit gastric acid secretion via CRH system. Am.J.Physiol.Gastrointest.Liver Physiol. 284 G963. PMID: 12584108. Szekereset al (2000) Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. J.Biol.Chem. 275 20247. PMID: 10811630. Minaminoet al (1985) Neuromedin U-8 and U-25: novel uterus stimulating and hypertensive peptides identified in porcine spinal cord. Biochem.Biophys.Res.Commun. 130 1078. PMID: 3841690. |