货号 | 2568/1 |
供应商 | Tocris |
生物活性 | Myelin oligodendrocyte glycoprotein (MOG) 35-55 is a minor component of CNS myelin. Produces a relapsing-remitting neurological disease with extensive plaque-like demyelination, common to the manifestations of multiple sclerosis. Induces strong T and B cell responses and is highly encephalitogenic. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 2581.97 |
分子式 | C118H177N35O29S |
可溶性/溶解性 | Soluble to 0.50 mg/ml in water |
CAS号 | 149635-73-4 |
序列号 | MEVGWYRSPFSRVVHLYRNGK |
参考文献 | Zhanget al (2004) T cell and antibody responses in remitting-relapsing experimental autoimmune encephalomyelitis in (C57BL/6xSJL) F1 mice. J.Neuroimmunol. 148 1. PMID: 14975581. Slavinet al (1998) Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. Autoimmunity 28 109. PMID: 9771980. Ichikawaet al (1996) Analysis of the fine B cell specificity during the chronic/relapsing course of a multiple sclerosis-like disease in Lewis rats injected with the encephalitogenic myelin oligodendrocyte glycoprotein peptide 35-55. J.Immunol. 157 919. PMID: 8752946. |