| 货号 | 3438/1 |
| 供应商 | Tocris |
| 生物活性 | Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no effect on food intake in free-feeding rats. Exhibits anxiolytic-like activity in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 609.73 |
| 分子式 | C34H39N7O4 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in 25% ethanol / water |
| CAS号 | 475498-26-1 |
| 序列号 | XRX (Modifications: X-1 = Ac-D-2-Nal, X-3 = 2-Nal & C-terminal amide) |
| 参考文献 | Chakiet al (2003) Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents. Eur.J.Pharmacol. 474 95. PMID: 12909200. |