| 货号 | 1535/1 |
| 供应商 | Tocris |
| 生物活性 | Novel mammalian endogenous peptide, homolog of substance P, that is a high affinity and selective agonist at the tachykinin NK1 receptor (Ki values are 0.175 and 560 nM for NK1 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1413.66 |
| 分子式 | C61H100N22O15S |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| CAS号 | 208041-90-1 |
| 序列号 | RSRTRQFYGLM (Modifications: Met-11 = C-terminal amide) |
| 参考文献 | Bellucciet al (2002) Pharmacological profile of the novel mammalian tachykinin hemokinin 1. Br.J.Pharmacol. 135 266. PMID: 11786503. Morteauet al (2001) Hemokinin 1 is a full agonist at the substance P receptor. Nat.Immunol. 2 1088. PMID: 11725292. Zhanget al (2000) Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat.Immunol. 1 392. PMID: 11062498. |