货号 | 2696/1 |
供应商 | Tocris |
生物活性 | Non-selective galanin receptor agonist (Ki values are 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 3164.48 |
分子式 | C141H211N43O41 |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
CAS号 | 114547-31-8 |
序列号 | GWTLNSAGYLLGPHAIDNHRSFSDKHGLT (Modifications: Thr-29 = C-terminal amide) |
参考文献 | Mazaratiet al (2006) Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: the effects of subtype-selective agonists and the role of G-protein-mediated signaling. J.Pharmacol.Exp.Ther. 318 700. PMID: 16699066. Brancheket al (2000) Galanin receptor subtypes. TiPS. 21109. Wanget al (1997) Cloning and expression characterization of a novel galanin receptor. J.Biol.Chem. 272 51. PMID: 8995226. |