c-JUN peptide (1 MG)
货号:
1989/1 基本售价:
3113.1 元 规格:
1 mg
产品信息
性能供应商 | Tocris |
生物活性 | Peptide comprising residues 33 - 57 of the JNK binding (δ) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of inflammatory gene expression. Specifically induces apoptosis in HeLa tumor cells. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 2743.55 |
分子式 | C121H210N36O34S |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
序列号 | ILKQSMTLNLADPVGSLKPHLRAKN |
参考文献 | Holzberget al (2003) Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN d domain induces apoptosis and affects a distinct set of interleukin-1 induced inflammatory genes. J.Biol.Chem. 278 40213. PMID: 12832416. |