| 货号 | 1891/1 |
| 别名 | Autoinhibitory peptide 457-482 |
| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 μM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 2930.34 |
| 分子式 | C124H205N39O39S2 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 148067-21-4 |
| 序列号 | ITSFEEAKGLDRINERMPPRRDAMP |
| 参考文献 | Perrinoet al (1995) Calcium regulation of calcineurin phosphatase activity by its B subunit and calmodulin. J.Biol.Chem. 270 340. PMID: 7814394. Yokoyama and Wang (1994) The role of the autoinhibitory domain in differential metal ion activation of calmodulin-stimulated phosphatase. FEBS Lett. 337 128. PMID: 8287965. Hashimotoet al (1990) Identification of an autoinhibitory domain in calcineurin. J.Biol.Chem. 265 1924. PMID: 2153670. |