货号 | 1894/1 |
供应商 | Tocris |
生物活性 | Amyloidβ-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to α7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1955.2 |
分子式 | C89H135N25O25 |
可溶性/溶解性 | Soluble to 0.70 mg/ml in water |
CAS号 | 107015-83-8 |
序列号 | VHHQKLVFFAEDVGSNK |
参考文献 | Freir and Herron (2003) Nicotine enhances the depressive actions of A β 1-40 on long-term potentiation in the rat hippocampal CA1 region in vivo. J.Neurophysiol. 89 2917. PMID: 12611941. Rayet al (1998) Binding of amyloid b-protein to intracellular brain proteins in rat and human. Neurochem.Res. 23 1277. PMID: 9804283. Floodet al (1994) An amyloid β-protein fragment, A b[12-28], equipotent impairs post-training memory processing when injected into different limbic system structures. Brain Res. 663 271. PMID: 7874511. |