货号 | 1846/1 |
供应商 | Tocris |
生物活性 | Annexin/lipocortin 1-mimetic peptide; inhibits leukocyte extravasation. Reduces neutrophil adhesion and emigration, and promotes detachment of neutrophils from activated mesenteric endothelium in mice in vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1351.58 |
分子式 | C63H94N14O17S |
可溶性/溶解性 | Soluble to 1 mg/ml in 20% acetonitrile / water |
CAS号 | 256447-08-2 |
序列号 | AMVSEFLKQAW (Modifications: Ala-1 = N-terminal Ac) |
参考文献 | Perrettiet al (2001) Involvement of the receptor for formylated peptides in the in vivo anti-migratory actions of annexin 1 and its mimetics. Am.J.Pathol. 158 1969. PMID: 11395373. Limet al (1998) Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1 Proc.Natl.Acad.Sci.U.S.A. 95 14535. PMID: 9826735. |