| 货号 | 3229/1 |
| 供应商 | Tocris |
| 生物活性 | Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin (Cat No. 3004) in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1046.23 |
| 分子式 | C50H75N15O10 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| 序列号 | RPPGFSPFR (Modifications: Phe-8 - Arg-9 peptide bond replaced with Ψ-(CH2-NH)) |
| 参考文献 | Leeb-Lundberget al (2005) International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27. PMID: 15734727. Marceauet al (2002) Kinin receptors: functional aspects. Int.Immunopharmacol. 2 1729. PMID: 12489786. Drapeauet al (1988) [Phe8Ψ(CH2-NH)Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II. Eur.J.Pharmacol. 155 193. PMID: 2907489. |