| 货号 | 3930/1 |
| 别名 | VIVIT peptide |
| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1683.94 |
| 分子式 | C75H118N20O22S |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| CAS号 | 249537-73-3 |
| 序列号 | MAGPHPVIVITGPHEE |
| 参考文献 | Nagamoto-Combs and Combs (2010) Microglial phenotype is regulated by activity of the transcription factor, NFAT (Nuclear Factor of Activated T Cells). J.Neurosci. 30 9641. PMID: 20631193. Roehrlet al (2004) Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules. Proc.Natl.Acad.Sci. 1017554. Aramburuet al (1999) Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. Science 285 2129. PMID: 10497131. |