| 货号 | 3819/10 |
| 别名 | (S)-2,3-Dihydro-7-hydroxy-2-(4-hydr |
| 供应商 | Tocris |
| 生物活性 | Potent ERβ agonist isolated from licorice root (EC50 = 36.5 nM for activation of the ERE tk-Luc reporter by ERβ in transfected U2OS cells). Displays 20-fold selectivity for ERβ; does not activate other nuclear receptors, including the androgen and glucocorticoid receptors. Displays anti-inflammatory effects. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 256.25 |
| 分子式 | C15H12O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Kimet al (2008) Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NK-kappaB-dependent iNOS and proinflammatory cytokines production. Br.J.Pharmacol. 154 165. PMID: 18332856. Mersereauet al (2008) Liquiritigenin is a plant-derived highly selective estrogen receptor beta agonist. Mol.Cell.Endocrinol. 283 49. PMID: 18177995. Yahara (1984) Flavonoid glucosides from licorice. Phytochemistry 232108. |