| 货号 | 2876/250U |
| 别名 | (5aS,12S,14aS)-1,2,3,5a,6,11,12,14a |
| 供应商 | Tocris |
| 生物活性 | Chemosensitizing agent; selectively reverses BCRP-mediated multidrug resistance to mitoxantrone (Cat. No. 4250), doxorubicin (Cat. No. 2252) and topotecan (Cat. No. 4562) in transfected MCF-7 cells. Does not reverse resistance in P-gp- or MRP-positive cells. Analog (Ko 143, Cat. No. 3241) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 379.45 |
| 分子式 | C22H25N3O3 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO |
| 参考文献 | Rabindranet al (2000) Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res. 60 (47). PMID: 10646850. Rabindranet al (1998) Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. Cancer Res. 58 5850. PMID: 9865745. |