AZD8055
货号：
2340-5 基本售价：
3012.5 元 规格：
5mg
产品信息
概述| 货号 | 2340-5 |
| 描述 | A potent, ATP-competitive inhibitor of mTOR kinase (both mTORC1 and mTORC2) with an IC₅₀ of 0.8 nM. AZD8055 displays excellent selectivity (~ 1,000-fold) against all class I PI3K isoforms and other members of the PI3K-like kinase family. In addition, it shows no significant activity against a panel of 260 kinases at concentrations up to 10 µM. AZD8055 inhibits the phosphorylation of mTORC1 substrates p70S6K and 4E-BP1 as well as phosphorylation of the mTORC2 substrate AKT and downstream proteins. |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20 ̊C |
| 外观 | Yellow solid |
