ZM 306416 hydrochloride (10 MG)
货号:
2499/10 基本售价:
2964.4 元 规格:
10 mg
产品信息
概述货号 | 2499/10 |
别名 | 4-[(4'-Chloro-2'-fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochloride |
性能供应商 | Tocris |
生物活性 | Inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase. Inhibits activity of KDR and FLT VEGF receptors (IC50 values are 100 nM and 2 μM respectively) and displays > 3-fold selectivity over FGFR-1. Orally active in vivo. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 370.21 |
分子式 | C16H13N3O2FCl.HCl |
可溶性/溶解性 | Soluble to 10 mM in DMSO |
CAS号 | 690206-97-4 |
参考文献 | Hennequinet al (1999) Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors. J.Med.Chem. 42 5369. PMID: 10639280. |