| 货号 | 4286/10 |
| 别名 | 4-[5-(4-Methoxyphenyl)-2-oxazolyl]- |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of microtubule polymerization in vitro. Interacts with tubulin dimers and promotes the accumulation of mammalian cells in apoptosis. Potentiates antiproliferative effects of vinblastine (Cat. No. 1256) in H2B-GFP HeLa cells. Originally thought to inhibit CENP-E ATPase activity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 353.37 |
| 分子式 | C23H15NO3 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| 参考文献 | Maiato and Logarinhoet al (2011) Motor-dependent and -independent roles of CENP-E at kinetochores: the cautionary tale of UA62784. Chem.Biol. 18 679. PMID: 21700202. Tcherniuket al (2011) UA62784 is a cytotoxic inhibitor of microtubules, not CENP-E. Chem.Biol. 18 631. PMID: 21609844. |