| 货号 | 2754/10 |
| 别名 | 2-[(Carboxycarbonyl)amino]-4,5,6,7- |
| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) (Ki values are 0.29, 59, 560, 1100, > 2000, > 2000 and > 2000 μM for PTP1B, CD45 D1D2, PTPβ, PTPε D1, SHP-1, PTPα D1 and LAR D1D2 respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 306.72 |
| 分子式 | C10H10N2O5S.HCl |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| CAS号 | 243967-42-2 |
| 参考文献 | Andersenet al (2002) Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B. J.Med.Chem. 45 4443. PMID: 12238924. Iversenet al (2000) Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B. J.Biol.Chem. 275 10300. PMID: 10744717. |