| 货号 | 3384/10 |
| 别名 | O-(2-Acetamido-2-deoxy-D-glucopyran |
| 供应商 | Tocris |
| 生物活性 | O-GlcNAc-β-N-acetylglucosaminidase (O-GlcNAcase) and β-hexosaminidase inhibitor (Ki values are 46 and 36 nM respectively) that increases O-GlcNAc levels ~ 2-fold in HT29 cells. Z-linked isomer is more potent than the Eisomer. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 353.33 |
| 分子式 | C15H19N3O7 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 132489-69-1 |
| 参考文献 | Perreiraet al (2006) Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry. Bioorg.Med.Chem. 14 837. PMID: 16214344. Macauleyet al(2005)O-GlcNAcase uses substrate-assisted catalysis. J.Biol.Chem. 280 25313. PMID: 15795231. Dong and Hart (1994) Purification and characterization of an O-GlcNAc selective N-acetyl-β-D-glucosaminidase from rat spleen cytosol. J.Biol.Chem. 269 19321. PMID: 8034696. |