PF 998425 (10 MG)
货号：
3923/10 基本售价：
2964.4 元 规格：
10 mg
产品信息
概述| 货号 | 3923/10 |
| 别名 | 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile |
性能| 供应商 | Tocris |
| 生物活性 | Selective non-steroidal androgen receptor (AR) antagonist (IC50 values are 26 nM and 90 nM in AR binding assays and cellular assays respectively). Displays low affinity for progesterone receptor (IC50 > 10 μM). Active in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 269.26 |
| 分子式 | C14H14F3NO |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 1076225-27-8 |
| 参考文献 | Liet al (2008) Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J.Med.Chem. 51 7010. PMID: 18921992. |
